Discovery of Broadly Neutralizing Antibodies (bNAbs) has given a great boost to HIV vaccine research. Study of bNAbs capable of neutralizing a broad array of different HIV strains is important for a number of reasons: (i) structures of antigens co-crystallized with bNAbs are used as templates in HIV vaccine design; (ii) bNAbs can be effective as therapeutics; (iii) preventive use of bNAbs is a promising direction in AIDS care. The goal of bNAber is to collect, analyze, compare and present bNAbs data, thus helping researchers to create HIV vaccine.
Search for anti-HIV bNAbs that fit the following criteria. All criteria are combined to create the resulting dataset.
Select Ab based on gp160 biding site:
Image used with permission from Cell Host Microbe.
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bNAber is a database, analysis, visualization, and data discovery tool for broadly neutralizing HIV-1 antibodies (bNAbs), and seeks to be a vital tool in the search for an AIDS vaccine.